who to write a thesis personal essay writers help in writing paper buy essays online help writing essays for college college application essay editing services i cant write my essay cheap custom essay writing help in essay writing essay writing help coursework planner write my essay fast writing research paper service essay writers needed order cheap essay write my essay wikipedia essay editor service help to write an essay what should i write my essay on buy an essay essay about community service cheap custom essays online someone write my essay for me custom note paper essay help introduction college research paper writing service affordable essay writing service need help writing my paper help in writing thesis buy a essay law essay writing service essay on customer service essay cheap write my essay reviews help me write a essay college application essay help online college paper writers do my essay cheap good thesis statements thesis defense advice essay writing service cheap essay writing help online best essay helper i need help on writing an essay buy a essay custom research papers writing service college admission essay editing services order cheap essay buy research paper cheap sat essay writing help need help writing an essay college paper help help with writing paper custom essay writing websites to buy research papers write my custom paper need help writing scholarship essay research paper writer online buy cheap essays online top essay writing service custom research paper writing services custom research paper services best essay writing write my english paper buying research papers online cheap essay writers best essay writing writing essay service write my business paper write my essay fast help in writing an essay essay writing services papers writing help premium essay writing service thesis editing services buy essay cheap online buy essay online cheap essay writing homework help Dr. Z answers: What is the cause of Hashimoto's Thyroiditis? - Dr. Zembroski

Dr. Z answers: What is the cause of Hashimoto’s Thyroiditis?

iStock_000000187667LargeWhenever a bacterium, virus, parasite, or grain of pollen enters the body, the white blood cells that make up the immune system mount an attack against the invader. That immune response happens when certain white blood cells form antibodies against the foreigner, while other white blood cells devour the bacteria or viruses, thus destroying them. These foreign invaders have proteins on their outer cell membranes that attract certain white blood cells called lymphocytes. The lymphocytes, through specific mechanisms, seek out and destroy foreign proteins like viruses, bacteria, and other aliens that come in contact with the body.

Autoimmunity occurs as a consequence of these same lymphocytes responding to proteins that make up our cells and tissues. Conditions such as Rheumatoid Arthritis, Celiac Disease, and Hashitmoto’s Thyroiditis are conditions of an autoimmune response. Hashimoto’s Thyroiditis more specifically occurs when the immune system goes after the thyroid. As a consequence of this the thyroid is impaired, producing less of the thyroid hormones T3, and T4. This autoimmune condition eventually creates hypothyroidism.

How does the immune system ‘all of a sudden’ go after its own body? What would cause such a response? Research states that many autoimmune conditions are triggered by previous infections, viral or bacterial. Viruses and bacteria are recognized by proteins found on their surfaces. The immune system produces antibodies to destroy the aliens, and then remain in circulation for some time. Unfortunately, certain cells and tissues in the body have similar proteins, which the antibodies identify as foreign, seek and destroy. 

Autoimmunity can also be caused by immune reactions to proteins found in certain foods. Again, the proteins in these common food sources cause the manufacturing of antibodies for those specific proteins, which also resemble the proteins found in and on our cells and tissues. The stress response also plays a role in autoimmunity, along with hormones, environmental toxins, and medications.

TH1 and TH2 immunity.
Most practitioners treat the thyroid in Hashimoto’s Thyroiditis, without addressing the autoimmune reaction. Unfortunately, this direction of treatment will perpetuate the disease. Shifting the immune system from a state of attack to one of surveillance is key to treating autoimmunity. This involves balancing the TH1 response and the TH2 response. TH1 cells notify the immune system that bacteria or viruses have entered the body. After the white blood cells seek and destroy the bacteria, the immune attack stops. TH2 cells produce antibodies against bacteria or viruses to overcome the infection. When bacteria or viruses come in, the antibodies are there to fight the infection. Under normal circumstances, the TH1 and TH2 response is balanced, switching back and forth according to the body’s need to deal with internal threats. 

In many autoimmune responses, the TH1 response becomes dominant; one example is Hashimoto’s Thyroiditis. The ideal treatment for Hashimoto’s is to balance the TH1 and TH2 response, instead of treating the tissue or organ targeted for the immune attack. Depending on the results of specific blood tests to uncover the imbalanced TH1 and TH2 response, a treatment plan should be implemented to normalize the response and help the areas of the body that have been the target for the autoimmune response.

Page, LM, du Toit, DF, Page, BJ, Understanding Autoimmune Disease—a review article for the layman, Division of Anatomy and Histology, University of Stellenbosch, Western Cape, RSA

BMJ volume 321 12 AUGUST 2000, Science commentary: Th1 and Th2 responses: what are they?

Submit a Comment

Your email address will not be published. Required fields are marked *